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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK2
All Species:
22.73
Human Site:
S766
Identified Species:
50
UniProt:
Q86UE8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UE8
NP_001106178.1
772
87661
S766
I
A
S
T
S
G
A
S
N
N
S
S
S
N
_
Chimpanzee
Pan troglodytes
XP_523598
848
95816
S842
I
A
S
T
S
G
A
S
N
N
S
S
S
N
_
Rhesus Macaque
Macaca mulatta
XP_001107302
907
100501
S901
I
A
S
T
S
G
A
S
N
N
S
S
S
N
_
Dog
Lupus familis
XP_548038
918
102784
S912
I
A
S
T
S
G
A
S
N
N
S
S
S
N
_
Cat
Felis silvestris
Mouse
Mus musculus
O55047
718
82242
S712
I
A
S
T
S
G
A
S
N
N
S
S
S
N
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
P711
L
A
A
S
P
T
P
P
T
S
S
V
I
S
Y
Chicken
Gallus gallus
XP_418070
750
85456
S744
I
A
S
T
S
G
S
S
N
N
S
S
S
N
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECX4
697
79286
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
Nematode Worm
Caenorhab. elegans
P34314
965
109255
R959
H
S
N
R
S
E
D
R
L
C
V
S
N
V
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
82.3
81.2
N.A.
92.4
N.A.
N.A.
68.6
94.1
N.A.
77.9
N.A.
N.A.
47.9
36.5
N.A.
Protein Similarity:
100
88.3
83
81.3
N.A.
92.7
N.A.
N.A.
77.7
95.8
N.A.
83.9
N.A.
N.A.
63.4
50.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
92.8
N.A.
0
N.A.
N.A.
0
14.2
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
53.3
100
N.A.
0
N.A.
N.A.
0
35.7
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
64
10
0
0
0
46
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
55
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
55
55
0
0
10
55
0
% N
% Pro:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
55
10
64
0
10
55
0
10
64
64
55
10
0
% S
% Thr:
0
0
0
55
0
10
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% _